Heart failure is a leading cause of death in Canada...
Anatomy
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Most Topular Stories
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A First For Ontario: Cardiac Stem Cell Transplant Performed At The Peter Munk Cardiac Centre
Cardiovascular / Cardiology News From Medical News Today27 Jan 2012 | 4:00 am -
A leukemia drug kills cancerous T-cells while sparing normal immunity, study suggests
ScienceDaily: Immune System News25 Jan 2012 | 9:19 amResearchers report that low-dose Campath (alemtuzumab) not only treats patients with L-CTCL but does so without increasing their risk of infections. -
Why are my OCD feelings so intense?
CNN.com - Health16 Aug 2011 | 11:28 amI have OCD. When I hear the sink faucet turn off, it makes a squeaking noise, and I feel tense and need to use antibacterial wipes on my hands. I also feel tense and need to use antibacterial wipes when I hear someone say the word "gas," when I see a red gas tank anywhere, when I see a gas nozzle at a gas station (or on TV), and the red color of a gas tank on anything plastic similar to a red gas tank. I also hate looking at sinks in the bathroom and kitchen because I feel tense and literally walk around the apartment covering my eyes so I do not see those objects when I am passing them. Why… -
Genetically modified food safe, animal study suggests
ScienceDaily: Immune System News24 Jan 2012 | 1:01 pmA three year feeding study has shown no adverse health effects in pigs fed genetically modified (GM) maize. The maize, which is a Bt-maize bred for its insect resistant properties, was sourced from Spain. -
Saving dogs with spinal cord injuries
ScienceDaily: Bone and Spine News18 Jan 2012 | 2:53 pmDogs with spinal cord injuries may soon benefit from an experimental drug currently being tested by researchers — work that they hope will one day help people with similar injuries.
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ScienceDaily: Human Biology News
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New information for flu fight: Researchers study RNA interference to determine host genes used by influenza for virus replication
27 Jan 2012 | 3:27 pmInfluenza virus can rapidly evolve from one form to another, complicating the effectiveness of vaccines and anti-viral drugs used to treat it. By first understanding the complex host cell pathways that the flu uses for replication, researchers are finding new strategies for therapies and vaccines, according to a new study. -
Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed
27 Jan 2012 | 1:09 pmIn both cell lines and mouse models, grape seed extract kills head and neck squamous cell carcinoma cells, while leaving healthy cells unharmed, new research shows. -
Scientists link evolved, mutated gene module to syndromic autism
26 Jan 2012 | 1:36 pmMedical researchers reports that newly discovered mutations in an evolved assembly of genes cause Joubert syndrome, a form of syndromic autism. -
Scientists map one of life's molecular mysteries: Visualisation of the molecular gateway across and into cellular membranes
26 Jan 2012 | 11:37 amAll living organisms are made up of cells, behind these intricate life forms lie complex cellular processes that allow our bodies to function. Researchers working on protein secretion -- a fundamental process in biology -- have revealed how protein channels in the membrane are activated by special signals contained in proteins destined for secretion. The results help explain the underlying mechanism responsible for the release of proteins such as hormones and antibodies into the blood stream. -
Limiting protein or certain amino acids before surgery may reduce risk of surgical complications
25 Jan 2012 | 1:31 pmLimiting certain essential nutrients for several days before surgery -- either protein or amino acids -- may reduce the risk of serious surgical complications such as heart attack or stroke, according to a new study.
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physiology « WordPress.com Tag Feed
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Most annoying urban myths debunked - part 7
8 Jan 2012 | 10:00 pmThere are countless urban myths floating around. Some are amusing, some are terrifying and some are just plain weird. But there are also plenty of urban myths that I just find utterly annoying. Most of them are things I’ve believed in myself in the past, but when thinking about it logically realising couldn’t be true. Which is why I find them so annoying! This is part seven – read part 1, part 2, part 3, part 4, part 5 and part 6 here. 13. Natural ingredients are better Ok. You know these adverts where they state that a particular food product only contain natural ingredients? And how… -
The Physiology of Hygiene
8 Jan 2012 | 11:29 amI love used books. There’s something about them, besides their smell, that makes them nifty an -
Sunday Special: Skin Health
8 Jan 2012 | 9:57 amI’ve covered so many different parts of the body; it blows my mind that I have yet to cover the skin (I mean it is the largest organ composing 16% of total body weight and 16-22 square feet!). It does deserve attention as we spend so much money on skin care and are all looking for the magic cure for young looking skin without the wrinkling and sagging and spend boo-coo bucks to have our skin tucked, pulled, stapled and whatever other crazy schemes they can come up with. Like most things, skin health care can be taken care of with a good nutrient-dense diet. What is the function… -
Singing Physiologically
6 Jan 2012 | 9:29 pmWhat I’d like to believe is that anyone can sing. Even if you’re born without perfect pi -
The Ayurveda of Relationships Chapter 1
6 Jan 2012 | 7:47 pmBy Arcane Ravenwolf The Ayurveda of Relationships for Women By Arcane Ravenwolf www.arcanealtruism.com Copyright © 2011 Arcane Ravenwolf Printed in the United States of America All rights reserved. No part of this book may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without permission in writing from the author. ISBN # 978-0-9826399-2-4 Non-fiction: Relationships/Dating, Non-fiction: Psychology, Non-fiction: Self Help This book is dedicated…
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CasesBlog - Medical and Health Blog
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How to evaluate a patient with chronic cough?
26 Jan 2012 | 11:52 pmInitial evaluation of chronic cough (defined as more than 8 weeks' duration in adults and 4 weeks in children) should include a chest radiography (CXR) in most adult patients. Patients who are taking an angiotensin-converting enzyme inhibitor (ACEi) should switch to a medication from another drug class. Differential diagnosis of cough, a simple mnemonic is GREAT BAD CAT TOM. Click here to enlarge the image: (GERD (reflux), Laryngopharyngeal Reflux (LPR), Rhinitis (both allergic and non-allergic) with post-nasal drip (upper airway cough syndrome), Embolism, e.g. PE in adults, Asthma, TB… -
Scabies - NHS patient education video
26 Jan 2012 | 11:52 pmFrom the NHS Choices YouTube channel: Scabies is a contagious skin infection which itches intensely. A GP talks about the causes, symptoms and treatment. From the memorable medical textbooks of the past: Medical textbooks were not always as dreary and as bland as they are now, according to BMJ. Some examples of lively, first person didactic tone come from J L Burton’s Essentials of Dermatology: "The simultaneous occurrence of scabies in a doctor and a nurse may mean that they have shared nothing more exciting than a patient with Norwegian scabies." References: Memorable medical textbooks of… -
"Doctors make mistakes. Can we talk about that?" ED physician Brian Goldman's TED talk
26 Jan 2012 | 7:45 amDr. Goldman asks if you know your surgeon's "batting average" of operations with good outcomes. He mentions the three words you never want to hear: "Do you remember?" It's a good TED talk: Every doctor makes mistakes (just like everyone does). But, says Dr. Goldman, medicine's culture of denial (and shame) keeps doctors from ever talking about those mistakes, or using them to learn and improve. Telling stories from his own long practice, he calls on doctors to start talking about being wrong. Here are some simple steps to avoid medical errors from a patient's perspective (source: CNN): 1. -
The Rise of the ePatient - presentation by Pew Internet Project
24 Jan 2012 | 7:20 amDirector Lee Rainie presented at Providence St. Joseph Medical Center in Burbank, California on January 12, 2012 on understanding social networking and online health information seeking: The Rise of the e-Patient View more presentations from Pew Research Center's Internet & American Life Project Link via via e-patients.net Here is how to facilitate the Rise of the ePhysican who works hand in hand with the ePatient: References: Social media in medicine: How to be a Twitter superstar and help your patients and your practice Posted at Clinical Cases and Images. Stay updated and subscribe, follow… -
Blogging is good for you - and for most people who read blogs
21 Jan 2012 | 11:36 amFrom The Economist: "Academic papers cited by bloggers are far more likely to be downloaded. Blogging economists are regarded more highly than non-bloggers with the same publishing record. The back-and-forth between bloggers resembles the informal chats, in university hallways and coffee rooms, that have always stimulated economic research, argues Paul Krugman, a Nobel-prize winning economist who blogs at the New York Times. But moving the conversation online means that far more people can take part. Despite the low barriers to entry, blogs do impose some intellectual standards. Errors of…
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Journal of Applied Physiology current issue
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Does skeletal muscle fiber branching play a role in the inability of old EDL dystrophic muscle to resist large passive stretches?
17 Jan 2012 | 9:00 am -
Reply to Scott, Sale, Greeves, and Fraser
17 Jan 2012 | 9:00 am -
Reply to Head
17 Jan 2012 | 9:00 am -
Automated regional analysis of B-mode ultrasound images of skeletal muscle movement
17 Jan 2012 | 9:00 amTo understand the functional significance of skeletal muscle anatomy, a method of quantifying local shape changes in different tissue structures during dynamic tasks is required. Taking advantage of the good spatial and temporal resolution of B-mode ultrasound imaging, we describe a method of automatically segmenting images into fascicle and aponeurosis regions and tracking movement of features, independently, in localized portions of each tissue. Ultrasound images (25 Hz) of the medial gastrocnemius muscle were collected from eight participants during ankle joint rotation (2° and… -
Effect of chronic intermittent hypoxia on noradrenergic activation of hypoglossal motoneurons
17 Jan 2012 | 9:00 amIn obstructive sleep apnea patients, elevated activity of the lingual muscles during wakefulness protects the upper airway against occlusions. A possibly related form of respiratory neuroplasticity is present in rats exposed to acute and chronic intermittent hypoxia (CIH). Since rats exposed to CIH have increased density of noradrenergic terminals and increased α1-adrenoceptor immunoreactivity in the hypoglossal (XII) nucleus, we investigated whether these anatomic indexes of increased noradrenergic innervation translate to increased sensitivity of XII motoneurons to noradrenergic…
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Cardiovascular / Cardiology News From Medical News Today
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A First For Ontario: Cardiac Stem Cell Transplant Performed At The Peter Munk Cardiac Centre
27 Jan 2012 | 4:00 amHeart failure is a leading cause of death in Canada... -
Patient-Centered Approach To Replacing Implantable Cardioverter-Defibrillators Suggested By Cardiologists
27 Jan 2012 | 2:00 amMore than 100,000 implantable cardioverter-defibrillators (ICDs) are implanted in the United States annually, fully a quarter of those are generator replacements simply because the battery is depleted. But are all those replacements necessary and should they actually be performed? Writing in the Jan... -
The Importance Of Metabolism In Understanding Health Benefits Of Cocoa Flavanols: Recent Study By Mars, Incorporated And Partners
27 Jan 2012 | 2:00 amA comprehensive investigation of flavanol absorption and metabolism has provided a critical step forward in our understanding of how cocoa flavanols work in the body to exert their circulatory and cardiovascular benefits... -
More Black Tea Lowers Blood Pressure
26 Jan 2012 | 4:00 pmTea, the second most consumed drink after water, may help lower blood pressure. Scientists at The University Of Western Australia and Unilever, state in Archives of Internal Medicine, that drinking black tea three times a day may drastically lower a person's systolic and diastolic blood pressure... -
Rapid Urbanization And Cultural Habits Responsible For High Prevalence Of Heart Disease In Gulf States
26 Jan 2012 | 11:00 amAlthough it is believed that rapid improvement in socio-economic conditions are responsible for the high prevalence of heart disease in the Gulf states, cultural factors are also to blame according to researchers. Professor Hani Najm, Vice-President of the Saudi Heart Association, whose yearly conference starts on Friday 27 January, explained: "We're sitting on a time bomb...
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MedPage Today Cardiovascular
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Once-Weekly Diabetes Treatment Gets FDA OK
27 Jan 2012 | 3:22 pmWASHINGTON (MedPage Today) -- The delay is over for the diabetes drug Bydureon (exenatide extended-release), with FDA approval making it the first once-weekly treatment for type 2 disease. -
Balloon Better Emboli Guard in Carotid Stenting (CME/CE)
27 Jan 2012 | 11:55 am(MedPage Today) -- Occluding the proximal carotid artery with a balloon may confer better protection against cerebral embolization than a filter device during carotid stenting, a randomized trial found. -
Sleep Problems Tied to CV, Metabolic Troubles (CME/CE)
27 Jan 2012 | 10:13 am(MedPage Today) -- Reported difficulty falling or staying asleep or sleeping too much was associated with heightened cardiometabolic risk, a large, nationally representative survey showed. -
Late Lumen Loss Less With Polymer-Free Stent (CME/CE)
26 Jan 2012 | 11:00 am(MedPage Today) -- A polymer-free drug-eluting stent appeared better at preventing late lumen loss than the paclitaxel-eluting stent Taxus, researchers found. -
Cardiologists Seek Ways to Improve Medicare Policy (with video)
26 Jan 2012 | 9:00 am(MedPage Today) -- The Centers for Medicare & Medicaid Services is revising its guidance on the use of a policy called "coverage with evidence development," and the American College of Cardiology has some ideas about how to improve the policy.
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Bones / Orthopedics News From Medical News Today
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New Standard For Vitamin D Testing To Ensure Accurate Test Results
27 Jan 2012 | 2:00 amAt a time of increasing concern about low vitamin D levels in the world's population and increased use of blood tests for the vitamin, scientists are reporting development of a much-needed reference material to assure that measurements of vitamin D levels are accurate. The report appears in ACS' journal Analytical Chemistry... -
Position Statement On The Role Of Vitamin D In Postmenopausal Women Published In Maturitas
27 Jan 2012 | 2:00 amElsevier, a world-leading provider of scientific, technical and medical information products and services, has announced the publication of a position statement by the European Menopause and Andropause Society (EMAS) in journal Maturitas on the role of vitamin D in postmenopausal women with summary recommendations. Vitamin D deficiency is common and may affect up to 70% of Europeans... -
Differences Discovered In Foot And Ankle Structure Between Sprinters And Non-Sprinters
26 Jan 2012 | 2:00 amThe skeletal structure of the foot and ankle differs significantly between human sprinters and non-sprinters, according to Penn State researchers. Their findings not only help explain why some people are faster runners than others, but also may be useful in helping people who have difficulty walking, such as older adults and children with cerebral palsy... -
Enhanced View Of Muscles Possible With New Tool
25 Jan 2012 | 3:00 amSimon Fraser University associate professor James Wakeling is adding to the arsenal of increasingly sophisticated medical imaging tools with a new signal-processing method for viewing muscle activation details that have never been seen before... -
Muscle Soreness Quantified By Researchers
25 Jan 2012 | 3:00 amQuantifying how sore a person is after a long workout is a challenge for doctors and researchers, but scientists from Loma Linda and Asuza Pacific Universities think they may have figured it out. Their research article describing a new technique to measure muscle soreness will be published in the Journal of Visualized Experiments (JoVE)...
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ScienceDaily: Bone and Spine News
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Leukemia cells are 'bad to the bone', research finds
26 Jan 2012 | 3:11 pmResearchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia. -
Saving dogs with spinal cord injuries
18 Jan 2012 | 2:53 pmDogs with spinal cord injuries may soon benefit from an experimental drug currently being tested by researchers — work that they hope will one day help people with similar injuries. -
Hip fractures: Coexisting medical conditions increase treatment costs and lengthen hospitalization, study finds
18 Jan 2012 | 10:20 amMore than 250,000 hip fractures occur every year in the U.S., often resulting in hospitalization, surgery, nursing-home admission, long-term disability, and/or extended periods of rehabilitation. Independent existing medical conditions (otherwise known as comorbidities) significantly increase the treatment cost and length of hospitalization for older adults who have sustained a hip fracture, according to a new study. -
Natural enzyme provides potential new approach for treating graft-vs.-host disease
17 Jan 2012 | 1:42 pmA natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants. -
Opioids erase memory traces of pain
13 Jan 2012 | 7:49 pmMedical researchers have discovered a previously unknown effect of opioids. The study shows that opioids not only temporarily relieve pain, but at the right dose can also erase memory traces of pain in the spinal cord and therefore eliminate a key cause of chronic pain.
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Immune System / Vaccines News From Medical News Today
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Skin Inflammation Controlled By Gatekeeper Signal
28 Jan 2012 | 2:00 amA new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online in the journal Immunity by Cell Press, identifies a "gatekeeper" that, when lost, can cause inflammatory skin disease in the absence of injury or infection... -
Mutation Drives Viral Sensors To Initiate Autoimmune Disease
28 Jan 2012 | 2:00 amA new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology... -
In Rheumatoid Arthritis, Steroids Prevent Protein Changes Seen In The Joints
28 Jan 2012 | 2:00 amRheumatoid arthritis (RA) is a chronic inflammatory disease where the body begins to attack the joints and organs of the body. Proteins within inflamed joints are often modified by citrullination, a process that converts the protein building block arginine into citrulline... -
Mathematically Modeling Tumor-Immune Interactions To Aid Cancer Therapy
27 Jan 2012 | 2:00 amCancer is one of the five leading causes of death. And yet, despite decades of research, there is no standardized first-line treatment for most cancers. In addition, disappointing results from predominant second-line treatments like chemotherapy have established the need for alternative methods... -
Chemical Contaminants Linked To Low Immune Response To Vaccines
25 Jan 2012 | 3:00 pmAlthough there have been some controversies in recent years, the routine childhood vaccination programs remain at the forefront of disease prevention in the community. Now, it appears that chemicals may affect the immune response to the vaccines, and reduce the immunity they provide...
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ScienceDaily: Immune System News
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Discovery of new vaccine approach for treatment of cancer
27 Jan 2012 | 1:05 pmScientists have developed a new vaccine to treat cancer at the pre-clinical level. They developed a new approach for treating the disease based on manipulating the immune response to malignant tumors. -
Heart of silk: Scientists use silk from the tasar silkworm as a scaffold for heart tissue
27 Jan 2012 | 12:59 pmDamaged human heart muscle cannot be regenerated. Scar tissue grows in place of the damaged muscle cells. Scientists are seeking to restore complete cardiac function with the help of artificial cardiac tissue. They have succeeded in loading cardiac muscle cells onto a three-dimensional scaffold, created using the silk produced by a tropical silkworm. -
A leukemia drug kills cancerous T-cells while sparing normal immunity, study suggests
25 Jan 2012 | 9:19 amResearchers report that low-dose Campath (alemtuzumab) not only treats patients with L-CTCL but does so without increasing their risk of infections. -
Increased exposure to compound widely used in food packaging associated with reduced immune response to vaccinations for children
24 Jan 2012 | 3:23 pmElevated exposures in children to perfluorinated compounds, which are widely used in manufacturing and food packaging, were associated with lower antibody responses to routine childhood immunizations, according to a new study. -
Genetically modified food safe, animal study suggests
24 Jan 2012 | 1:01 pmA three year feeding study has shown no adverse health effects in pigs fed genetically modified (GM) maize. The maize, which is a Bt-maize bred for its insect resistant properties, was sourced from Spain.
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Lymphology/Lymphedema News From Medical News Today
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New, Noninvasive Way To Identify Lymph Node Metastasis
15 Jan 2012 | 2:00 amUsing two cell surface markers found to be highly expressed in breast cancer lymph node metastases, researchers at Moffitt Cancer Center, working with colleagues at other institutions, have developed targeted, fluorescent molecular imaging probes that can non-invasively detect breast cancer lymph node metastases... -
Significant Cost Savings Associated With Emergence Of Prospective Surveillance Model As Standard Of Care For Breast Cancer Treatment
9 Jan 2012 | 2:00 amEarly diagnosis and treatment of breast cancer-related lymphedema by a physical therapist can significantly reduce costs and the need for intensive rehabilitation, according to an article published in the January issue of Physical Therapy (PTJ), the scientific journal of the American Physical Therapy Association (APTA)... -
New Treatment Direction For Rare Metabolic Diseases
3 Jan 2012 | 3:00 amA research team led by biochemist Scott Garman at the University of Massachusetts Amherst has discovered a key interaction at the heart of a promising new treatment for a rare childhood metabolic disorder known as Fabry disease. The discovery will help understanding of other protein-folding disorders such as Alzheimer's, Parkinson's and Huntington's diseases, as well... -
New Treatment Direction For Rare Metabolic Diseases
23 Dec 2011 | 3:00 amA research team led by biochemist Scott Garman at the University of Massachusetts Amherst has discovered a key interaction at the heart of a promising new treatment for a rare childhood metabolic disorder known as Fabry disease. The discovery will help understanding of other protein-folding disorders such as Alzheimer's, Parkinson's and Huntington's diseases, as well... -
Removal Of Lymph Nodes During Surgery For Thyroid Cancer May Be Beneficial
22 Dec 2011 | 2:00 amPapillary thyroid cancer accounts for the majority of all thyroid malignancies, which primarily impact women. A new study indicates that routinely removing lymph nodes in the neck in these cancer patients may help prevent the disease from coming back...
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ScienceDaily: Nervous System News
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Possible new treatment for Rett Syndrome
27 Jan 2012 | 4:48 pmResearchers have discovered that a molecule critical to the development and plasticity of nerve cells – brain-derived neurotrophic factor -- is severely lacking in brainstem neurons in mutations leading to Rett syndrome, a neurological developmental disorder. The finding has implications for the treatment of neurological disorders, including Rett syndrome that affects one in 10,000 baby girls. -
Scientists identify protein that contributes to symptoms of Parkinson's disease
25 Jan 2012 | 12:26 pmScientists have identified a protein that exacerbates symptoms of Parkinson's disease -- a discovery that could one day lead to new treatments for people who suffer from this devastating neurodegenerative illness. -
Appetite accomplice: Ghrelin receptor alters dopamine signaling
25 Jan 2012 | 12:26 pmNew research reveals a fascinating and unexpected molecular partnership within the brain neurons that regulate appetite. The study resolves a paradox regarding a receptor without its hormone and may lead to more specific therapeutic interventions for obesity and disorders of dopamine signaling. -
Mechanism sheds light on how the brain adapts to stress
25 Jan 2012 | 12:26 pmScientists now have a better understanding of the way that stress impacts the brain. New research reveals pioneering evidence for a new mechanism of stress adaptation and may eventually lead to a better understanding of why prolonged and repeated exposure to stress can lead to anxiety disorders and depression. -
In schizophrenia research, a path to the brain through the nose
25 Jan 2012 | 8:11 amA significant obstacle to progress in understanding psychiatric disorders is the difficulty in obtaining living brain tissue for study so that disease processes can be studied directly. Recent advances in basic cellular neuroscience now suggest that, for some purposes, cultured neural stem cells may be studied in order to research psychiatric disease mechanisms. But where can one obtain these cells outside of the brain?
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CNN.com - Health
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Can a nerve stimulator stop my back pain?
16 Jan 2012 | 6:10 amI have had severe, chronic back and sciatic pain for many years. My particular problems cannot be resolved surgically. Nerve blocks and other minimally invasive procedures have been partially successful in temporarily reducing the pain. -
Could my bipolar brother develop schizophrenia?
23 Aug 2011 | 12:12 pmI was wondering if my brother, who we have been told is bipolar, could develop schizophrenia? My uncle, my mom's brother, was schizophrenic and unfortunately fell victim to the mental illness. We are aware that there have been some mental health issues with males on my mother's side of the family, so could it be possible that he could be schizophrenic as well as bipolar? -
Why are my OCD feelings so intense?
16 Aug 2011 | 11:28 amI have OCD. When I hear the sink faucet turn off, it makes a squeaking noise, and I feel tense and need to use antibacterial wipes on my hands. I also feel tense and need to use antibacterial wipes when I hear someone say the word "gas," when I see a red gas tank anywhere, when I see a gas nozzle at a gas station (or on TV), and the red color of a gas tank on anything plastic similar to a red gas tank. I also hate looking at sinks in the bathroom and kitchen because I feel tense and literally walk around the apartment covering my eyes so I do not see those objects when I am passing them. Why… -
Could bump on my wrist be a ganglion cyst?
6 Jul 2011 | 10:55 amSomething is wrong with my left wrist. When I bend it or touch the area or put pressure on it, it hurts really badly. Could this be a ganglion cyst? What should I do about it? -
How can I stop this high-pitched noise?
29 Jun 2011 | 6:13 amTwo weeks ago I began having a really disturbing sound in my ears. The noise is constant, with high frequency. I can hear it almost all the time, especially in the mornings. Why is this happening? I have not had any accidents. What can I do about it?

